Testosterone Enanthate Primoteston Depot 250 mg 1 ml

In stock
$39.88
Please consult your physician before taking any medication. GENERIC NAME: Testosterone. And dosage form: Each vial of oil solution contains: Testosterone enanthate mg 250.00 .......... Vehicle qs ................................... 1.00 ml INDICATIONS: In men: Hypogonadism; potency disorders; male menopause, aplastic anemia. In women: adjuvant treatment of progressive breast carcinoma in postmenopausal. Pharmacokinetics in Humans: Pharmacodynamic Properties Primoteston DEPOT contains a derivative of the hormone testosterone male sexual nature as an active ingredient. Accordingly, testosterone enanthate has the ability to eliminate symptoms due to androgen deficiency. Pharmacokinetics Testosterone enanthate: After intramuscular administration, testosterone enanthate is systemically available in its entirety. The compound is gradually released from the reservoir with a half life of about 4.5 days and is metabolised to testosterone and ENANTHIC acid. After intramuscular administration of 250 mg of testosterone enanthate young men, 1.5 to 3 days later they were able to determine peak testosterone concentrations of 20 ng / ml. The levels of testosterone in the plasma decreased with a half-life of about 4.5 days, which corresponds to the rate of release from the reservoir. Testosterone concentrations> 2 ng / ml were maintained for 20 days and those> 1 ng / ml for 26 days. At a dose of 250 mg of testosterone enanthate, patients received a total dose of 180 mg of testosterone. By the time the peak serum levels are achieved, the daily average dose after 1 and 2 weeks and 4 correspond to 12 mg of testosterone, respectively. Testosterone is completely released from the term deposit approximately 4 weeks after administration of the drug. Testosterone that is generated by degradation of the ester from testosterone enanthate metabolized and excreted in the same way as the endogenous testosterone. The enanthic acid is metabolized by β-oxidation in the same way that other aliphatic carboxylic acids. The metabolic clearance of testosterone was calculated in 16 ± 7 ml / min / kg and refers to liver and extra hepatic metabolism of testosterone. Testosterone metabolites are eliminated with a half-life of 7.8 days. Approximately 90% is excreted by the kidneys and about 10% in the bile. Testosterone is set at a high rate to serum proteins, including albumin, and sex hormone binding globulin (SHBG). The absolute bioavailability of Testosterone from ester is almost full, indicating a rapid and efficient degradation of the ester. The injection of 250 mg testosterone enanthate every 3 to 4 weeks causes no clinically significant accumulation of testosterone in serum.

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